Overview of Prostate Cancer Treatment

The testosterone hormone controls prostates and generates semen. Ejaculation comes out of the urethra which contains sperm. When cells in the prostate gland develop uncontrollably and form a tumor, it is called prostate cancer. Cancer has the ability to invade every organ in the body to which we say the cancer has metastasized. Prostate cancer has been the top most cancer in men. It is estimated to reach a projection rate of 30,185 by the year 2020 in India. Although it is slow in progress, it is the third leading cause of death in men. When prostate cancer is suspected, a tissue biopsy is the gold standard for diagnostic purposes. Other screening tools include MRI, FMRI, and biomarkers such as PSA that are positively correlated with the diagnosis of prostate cancer and have revolutionized the epidemiology of this disease. Advanced treatments have been proven to improve quality of life and patient satisfaction. Active surveillance, surgery, radiation therapy, hormone therapy, chemotherapy, and immunotherapy are all potential treatments for prostate cancer. Technology advancement has made so much progress in disclosing the etiology and risk factors for prostate cancer. Lifestyle modification, including physical activity, low saturated fats, and high fruit and vegetable intake, can be the best prevention against prostate cancer. Thus, the choice of therapy involves weighing the pros and cons associated with treatments for localized prostate cancer.

Types of Prostate Cancer Treatment

  • Chemotherapy
  • Immunotherapy
  • Surgery
  • Radiation therapy
  • Hormonal therapy
  • Active surveillance
  • Focal therapies

Chemotherapy

Chemotherapy is the use of medications to kill cancer cells, typically by preventing the growth, division, and production of new cancer cells. Both with metastatic prostate cancer who have recently been diagnosed and who, with constantly growing tumor may benefit from chemotherapy.

Immunotherapy

Immunotherapy strengthens your immune system's capacity to attack cancer cells in order to combat the disease. Sipuleucel-T  vaccination therapy may be an option for some men with constantly growing  metastatic prostate cancer who have no or very few cancer symptoms and typically have not received chemotherapy.

Surgery

Some surgical procedures used for prostate cancer in India are as follows:

Prostatectomy: the removal of a prostate gland and seminal vesicles alongside lymph nodes.

Laparoscopic prostatectomy: the less painful by small incision with insertion of camera and robotic instrument to remove prostate gland.

Bilateral orchiectomy: the surgical removal of both testicles in advanced stages of the disease.

Radiation Therapy

External-beam radiation therapy: it uses the machine outside which projects the x-rays directly on the cancerous cells. 

Proton therapy: is also a type of external radiation but it differs in the way that it uses protons instead of the beam of x-rays.

Brachytherapy: this is internal radiation which involves the insertion of a radioactive material into the cancer area. The radiation from the radioactive material kills the cancerous cell.

Hormonal Therapy

In hormone therapy some medications are used to block the production of testosterone hormone. Some of these medications include:

LHRH agonists: luteinizing hormone releasing hormone agonists are used to block the testosterone production by the testicles.

AR inhibitors: androgen receptor inhibitors block the testosterone effect by inhibiting the receptors used for its functioning.

Active Surveillance

Patients who are diagnosed at an early stage and have a very low risk are usually not treated because of the adverse effects of treatments such as radiation and chemotherapy. So, patients are usually monitored gradually for any worsening signs. If the cancer worsens, typical treatment should then start.

Focal Therapies

Cryosurgery: This treatment involves local heat and cold therapy to destroy cancer cells without treating normal cells. It is used for low- to moderate-risk cancers.

HIFU: (high-intensity focal ultrasound) uses sound radiation to destroy cancer cells and limit the effect on normal cells. But it may not be the treatment of choice for some people despite its appealing qualities.

Diagnosis of Prostate Cancer Treatment

PSA Test

Prostate specific antigen (PSA) levels in the blood are determined by this blood test. The prostate produces a chemical called PSA and men with prostate cancer may have elevated blood PSA concentrations.

DRA

A doctor does a digital rectal examination (DRE) by inserting a gloved, greased finger into a man's rectum to feel the prostate for anything unusual, like cancer.

Biopsy

A biopsy is the removal of a tiny sample of tissue for microscopic analysis. The prostate will be sampled for biopsies in a number of locations. This is carried out to guarantee that a high-quality sample is obtained for analysis.

Transrectal Ultrasound TRUS

The prostate is examined by a probe that a doctor puts into the rectum using sound waves that the prostate reflects. The reflecting waves can give the idea of the poor morphology.

MRI (magnetic resonance imaging)

The size of the tumor can be determined using an MRI, and the prostate or the entire body might be the focus of the scan. Prior to the scan, a patient is given an injection of a specific dye called contrast medium into a vein in order to provide a clearer image.

Prostate Cancer Treatment Cost in India

The patients with other deadly diseases, PSA levels, the presentation of the cancer cells in the prostate and stage of the cancer all affect the recommended course of treatment for prostate cancer in India. The average cost of treating prostate cancer in India ranges from 5443 USD to 9072 USD. The cost of treating prostate cancer in India varies depending on the facility and the city. 

Here are several surgical procedures and their associated costs:

Treatment Costs in India Min in USD Max in USD
Laparoscopic prostatectomy 5806 USD 6653 USD
Robot assisted prostatectomy 8467 USD 9073 USD
Radical prostatectomy 3628 USD 4838 USD

Cost ranges for different procedures in India:

Treatment Costs in India Min in USD Max in USD
Surgery 847 USD 1427 USD
Chemotherapy 120 USD 1814 USD
Radiation therapy 363 USD 24192  USD
Others 12096 USD 9072 USD

 

Symptoms & Risk Factors of Prostate Cancer Treatment

  • Having a poor urine flow.
  • Difficulty starting to urinate.
  • Straining.
  • Urinary incontinence.
  • Need to get up frequently during the night to urinate.
  • UTI (urinary tract infection).
  • Blood in urine.
  • Enlarged prostate gland.
  • Pain during urination.
  • Inability to erect penis.

Risk Factors of Prostate Cancer

Age

Prostate cancer is frequently present in older adults usually after 50 years of age.

Family History

It has been studied that about 20% of victims of prostate cancer report a family history, which may develop because of genes and also for a same subjection to certain carcinogens, drugs and common lifestyle habits.

Genetic Factors

The X chromosome is also thought to play a role in the inheritance of prostate cancer. The X chromosomes have the androgen receptors so they show a positive correlation with prostate cancer.

Diet

Unrefined animal fat: Numerous ecological research studies have revealed a link between meat, fat, and dairy consumption per capita and prostate cancer.

Red Meat: The positive correlation between using the excess of red meat and prostate cancer have been shown under research studies.
Calcium, dairy products: dairy products have often been linked to an increased risk of prostate cancer.  Males are at an increased risk of prostate cancer from both calcium from supplements and dairy.

Vitamin D deficiency: it has been suggesting that vitamin D deficiency might increase prostate cancer risk.

Alcohol Consumption and Smoking

More than 3 drinks per day shows risk factors of many types of cancers including prostate cancer. The link between smoking and increased risk of prostate cancer may be hormonal or hereditary in nature. For instance, men who smoke tend to have greater amounts of circulating sex hormones, which may raise the risk of prostate cancer.

Obesity

High body mass index (BMI) is linked to more aggressive and advanced prostate cancer as well as a worse prognosis.

Top Hospitals for Prostate Cancer in India

Shaping the future of the healthcare institution and establishing the path to accomplishment.

Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute Andheri West, Mumbai,India

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Fortis Hospital, Bannerghatta Road Bengaluru,India

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Max Super Speciality Hospital, Vaishali Ghaziabad,India

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Max Super Speciality Hospital Dehradun Dehradun,India

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Burjeel Medical Hospital City Abu Dhabi,UAE

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Jaypee Hospitals, Noida, Uttar Pradesh India

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Metro Hospital Faridabad,India,

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Indraprastha Apollo Hospital New Delhi

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Metro Hospital Faridabad,India,

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Top Doctors for Prostate Cancer in India

Empower your Health with the Expertise of Leading Medical Professionals.

Dr. Surender Kumar Dabas

Department of Surgical Oncology & Oncology

Senior Director

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Dr. H. S. Bhatyal

Department of Urology

Director Urology

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Dr. Pankaj Maheshwari N

Department of General Surgery

Consultant – General Surgery

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Dr. Pankaj Maheshwari N

Department of General Surgery

Consultant – General Surgery

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Dr. Arun R Warrier

Department of Medical Oncology

Consultant

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Treatment Costs for Prostate Cancer

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FAQ's of Prostate Cancer Treatment

There are no known reasons as to why a person will have prostate cancer. It is a cancer that occurs when some of the cells in the prostate gland become abnormal.

If detected at a later stage and the cancer has spread to other organs as well, the disease can be quite deadly.

Life expectancy of a man living with prostate cancer without any treatment is 4 years.

Prostate cancer is uncommon among men under the age of 40 and is more common among men who are above 50 years of age.